Race Result
| GP n. 356 - 27/09/1981 - Grand Prix of Canada Circuit Gilles Villeneuve |
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| Winner: | Jacques Laffite / Ligier-Matra - 2:01'25.20 | ||||||
| Pole Position: | Nelson Piquet / Brabham-Ford - 1:29.211 | ||||||
| Fastest Lap: | John Watson / McLaren-Ford - 1:49.475 | ||||||
| Pos | Nš | Driver | Constructor | Laps | Time/Retired | Grid | Points |
| 1 | 26 |  Jacques Laffite |
Ligier-Matra | 63 | 2:01'25.20 | 10 | 9 |
| 2 | 7 |  John Watson |
McLaren-Ford | 63 | + 6.23 | 9 | 6 |
| 3 | 27 |  Gilles Villeneuve |
Ferrari | 63 | + 1'50.27 | 11 | 4 |
| 4 | 23 |  Bruno Giacomelli |
Alfa Romeo | 62 | + 1 lap | 15 | 3 |
| 5 | 5 |  Nelson Piquet |
Brabham-Ford | 62 | + 1 lap | 1 | 2 |
| 6 | 11 | Elio de Angelis |
Lotus-Ford | 62 | + 1 lap | 7 | 1 |
| 7 | 22 |  Mario Andretti |
Alfa Romeo | 62 | + 1 lap | 16 | 0 |
| 8 | 17 |  Derek Daly |
March-Ford | 61 | + 2 laps | 20 | 0 |
| 9 | 33 |  Marc Surer |
Theodore-Ford | 61 | + 2 laps | 19 | 0 |
| 10 | 2 |  Carlos Reutemann |
Williams-Ford | 60 | + 3 laps | 2 | 0 |
| 11 | 4 | Michele Alboreto |
Tyrrell-Ford | 59 | + 4 laps | 22 | 0 |
| 12 | 3 | Eddie Cheever |
Tyrrell-Ford | 56 | engine | 14 | 0 |
| Ret | 8 | Andrea de Cesaris |
McLaren-Ford | 51 | spun off | 13 | 0 |
| Ret | 15 | Alain Prost |
Renault | 48 | collision | 4 | 0 |
| Ret | 12 | Nigel Mansell |
Lotus-Ford | 45 | collision | 5 | 0 |
| Ret | 9 |  Slim Borgudd |
ATS-Ford | 40 | spun off | 21 | 0 |
| Ret | 6 |  Hector Rebaque |
Brabham-Ford | 35 | spun off | 6 | 0 |
| Ret | 32 | Jean Pierre Jarier |
Osella-Ford | 26 | collision | 23 | 0 |
| Ret | 28 | Didier Pironi |
Ferrari | 24 | ignition | 12 | 0 |
| Ret | 1 |  Alan Jones |
Williams-Ford | 24 | handling | 3 | 0 |
| Ret | 14 |  Eliseo Salazar |
Ensign-Ford | 8 | spun off | 24 | 0 |
| Ret | 29 | Riccardo Patrese |
Arrows-Ford | 6 | spun off | 18 | 0 |
| Ret | 25 | Patrick Tambay |
Ligier-Matra | 6 | spun off | 17 | 0 |
| Ret | 16 | Rene Arnoux |
Renault | 0 | collision | 8 | 0 |
| Dnq | 30 | Jacques Villeneuve Sr |
Arrows-Ford | did not qualify | 0 | ||
| Dnq | 20 |  Keke Rosberg |
Fittipaldi-Ford | did not qualify | 0 | ||
| Dnq | 21 | Chico Serra |
Fittipaldi-Ford | did not qualify | 0 | ||
| Dnq | 31 | Beppe Gabbiani |
Osella-Ford | did not qualify | 0 | ||
| Dnq | 35 | Brian Henton |
Toleman-Hart | did not qualify | 0 | ||
| Dnq | 36 | Derek Warwick |
Toleman-Hart | did not qualify | 0 | ||