Race Result
| GP n. 348 - 31/05/1981 - Grand Prix of Monaco Circuit de Monte Carlo |
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| Winner: | Gilles Villeneuve / Ferrari - 1:54'23.38 | ||||||
| Pole Position: | Nelson Piquet / Brabham-Ford - 1:25.710 | ||||||
| Fastest Lap: | Alan Jones / Williams-Ford - 1:27.47 | ||||||
| Pos | Nš | Driver | Constructor | Laps | Time/Retired | Grid | Points |
| 1 | 27 |  Gilles Villeneuve |
Ferrari | 76 | 1:54'23.38 | 2 | 9 |
| 2 | 1 |  Alan Jones |
Williams-Ford | 76 | + 39.91 | 7 | 6 |
| 3 | 26 |  Jacques Laffite |
Ligier-Matra | 76 | + 1'29.24 | 8 | 4 |
| 4 | 28 | Didier Pironi |
Ferrari | 75 | + 1 lap | 17 | 3 |
| 5 | 3 |  Eddie Cheever |
Tyrrell-Ford | 74 | + 2 laps | 15 | 2 |
| 6 | 14 |  Marc Surer |
Ensign-Ford | 74 | + 2 laps | 19 | 1 |
| 7 | 33 | Patrick Tambay |
Theodore-Ford | 72 | + 4 laps | 16 | 0 |
| Ret | 5 |  Nelson Piquet |
Brabham-Ford | 53 | spun off | 1 | 0 |
| Ret | 7 |  John Watson |
McLaren-Ford | 52 | engine | 10 | 0 |
| Ret | 23 |  Bruno Giacomelli |
Alfa Romeo | 50 | collision | 18 | 0 |
| Ret | 4 | Michele Alboreto |
Tyrrell-Ford | 50 | collision | 20 | 0 |
| Ret | 15 | Alain Prost |
Renault | 45 | engine | 9 | 0 |
| Ret | 2 |  Carlos Reutemann |
Williams-Ford | 33 | gear box | 4 | 0 |
| Ret | 11 | Elio de Angelis |
Lotus-Ford | 32 | engine | 6 | 0 |
| Ret | 16 | Rene Arnoux |
Renault | 32 | spun off | 13 | 0 |
| Ret | 29 | Riccardo Patrese |
Arrows-Ford | 29 | gear box | 5 | 0 |
| Ret | 12 | Nigel Mansell |
Lotus-Ford | 15 | suspension | 3 | 0 |
| Ret | 30 | Siegfried Stohr |
Arrows-Ford | 14 | fuel system | 14 | 0 |
| Ret | 22 | Mario Andretti |
Alfa Romeo | 0 | collision | 12 | 0 |
| Ret | 8 | Andrea de Cesaris |
McLaren-Ford | 0 | collision | 11 | 0 |
| Dnq | 10 |  Slim Borgudd |
ATS-Ford | did not qualify | 0 | ||
| Dnq | 6 |  Hector Rebaque |
Brabham-Ford | did not qualify | 0 | ||
| Dnq | 20 |  Keke Rosberg |
Fittipaldi-Ford | did not qualify | 0 | ||
| Dnq | 21 | Chico Serra |
Fittipaldi-Ford | did not qualify | 0 | ||
| Dnq | 25 | Jean Pierre Jabouille |
Ligier-Matra | did not qualify | 0 | ||
| Dnq | 17 |  Eliseo Salazar |
March-Ford | did not qualify | 0 | ||
| Dnq | 18 |  Derek Daly |
March-Ford | did not qualify | 0 | ||
| Dnq | 31 | Beppe Gabbiani |
Osella-Ford | did not qualify | 0 | ||
| Dnq | 32 | Piercarlo Ghinzani |
Osella-Ford | did not qualify | 0 | ||
| Dnq | 35 | Brian Henton |
Toleman-Hart | did not qualify | 0 | ||
| Dnq | 36 | Derek Warwick |
Toleman-Hart | did not qualify | 0 | ||