Race Result
| GP n. 349 - 21/06/1981 - Grand Prix of Spain Circuito Permanente del Járama |
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| Winner: | Gilles Villeneuve / Ferrari - 1:46'35.01 | ||||||
| Pole Position: | Jacques Laffite / Ligier-Matra - 1:13.754 | ||||||
| Fastest Lap: | Alan Jones / Williams-Ford - 1:17.818 | ||||||
| Pos | Nº | Driver | Constructor | Laps | Time/Retired | Grid | Points |
| 1 | 27 |  Gilles Villeneuve |
Ferrari | 80 | 1:46'35.01 | 7 | 9 |
| 2 | 26 |  Jacques Laffite |
Ligier-Matra | 80 | + 0.22 | 1 | 6 |
| 3 | 7 |  John Watson |
McLaren-Ford | 80 | + 0.58 | 4 | 4 |
| 4 | 2 |  Carlos Reutemann |
Williams-Ford | 80 | + 1.01 | 3 | 3 |
| 5 | 11 |  Elio de Angelis |
Lotus-Ford | 80 | + 1.24 | 10 | 2 |
| 6 | 12 | Nigel Mansell |
Lotus-Ford | 80 | + 28.58 | 11 | 1 |
| 7 | 1 |  Alan Jones |
Williams-Ford | 80 | + 56.58 | 2 | 0 |
| 8 | 22 |  Mario Andretti |
Alfa Romeo | 80 | + 1'00.80 | 8 | 0 |
| 9 | 16 | Rene Arnoux |
Renault | 80 | + 1'07.08 | 17 | 0 |
| 10 | 23 | Bruno Giacomelli |
Alfa Romeo | 80 | + 1'13.65 | 6 | 0 |
| 11 | 21 |  Chico Serra |
Fittipaldi-Ford | 79 | + 1 lap | 21 | 0 |
| 12 | 20 |  Keke Rosberg |
Fittipaldi-Ford | 78 | + 2 laps | 15 | 0 |
| 13 | 33 | Patrick Tambay |
Theodore-Ford | 78 | + 2 laps | 16 | 0 |
| 14 | 14 |  Eliseo Salazar |
Ensign-Ford | 77 | + 3 laps | 24 | 0 |
| 15 | 28 | Didier Pironi |
Ferrari | 76 | + 4 laps | 13 | 0 |
| 16 | 17 |  Derek Daly |
March-Ford | 75 | + 5 laps | 22 | 0 |
| Nc | 3 | Eddie Cheever |
Tyrrell-Ford | 62 | not classified | 20 | 0 |
| Ret | 25 | Jean Pierre Jabouille |
Ligier-Matra | 51 | brakes | 19 | 0 |
| Ret | 6 |  Hector Rebaque |
Brabham-Ford | 46 | gear box | 18 | 0 |
| Ret | 30 | Siegfried Stohr |
Arrows-Ford | 43 | ignition | 23 | 0 |
| Ret | 5 | Nelson Piquet |
Brabham-Ford | 43 | accident | 9 | 0 |
| Ret | 15 | Alain Prost |
Renault | 28 | spun off | 5 | 0 |
| Ret | 29 | Riccardo Patrese |
Arrows-Ford | 21 | brakes | 12 | 0 |
| Ret | 8 | Andrea de Cesaris |
McLaren-Ford | 9 | accident | 14 | 0 |
| Dnq | 9 |  Slim Borgudd |
ATS-Ford | did not qualify | 0 | ||
| Dnq | 31 | Beppe Gabbiani |
Osella-Ford | did not qualify | 0 | ||
| Dnq | 32 | Giorgio Francia |
Osella-Ford | did not qualify | 0 | ||
| Dnq | 35 | Brian Henton |
Toleman-Hart | did not qualify | 0 | ||
| Dnq | 36 | Derek Warwick |
Toleman-Hart | did not qualify | 0 | ||
| Dnq | 4 | Michele Alboreto |
Tyrrell-Ford | did not qualify | 0 | ||